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All these trials were designed to evaluate the primary outcome of 3-MACE defined as cardiovascular death, nonfatal myocardial infarct, and nonfatal stroke, except for the ELIXA trial of exenatide ER, which included hospitalization for unstable angina as an additional component of the 4-MACE composite outcomes

Mortality gains from these drugs could change how we view metabolic risks in underwriting and unlock new opportunities to design and offer products centered around different metabolic risk profiles

Any discussion of blood pressure in this article is intended as general consumer education - it is not a substitute for evaluation by a licensed healthcare professional and should not be interpreted as guidance for treating, managing, or diagnosing any health condition