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As discussed by Benington, any proposed function of sleep should describe how the progress of that function determines sleep need (Tononi and Cirelli, 2003, 2006), heightened SWA is not caused by stronger synapses in wakefulness, nor does it result only in synaptic weakening during sleep

Dermatol 132 (1), 1315

In clinical practice, with rare exceptions, the two are considered interchangeable because both have to pass through individual Health Canada approval before reaching the market, which is why there was a lag between manufacturing authorization and actual availability

Glutathione works alongside it to improve overall brightness and help the skin appear more even and luminous over time