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The results of this paper showed that mitochondrial dysfunction associated with cell apoptosis including membrane potential loss, down-regulation of Bcl-2 and up-regulation of Bax, activation of caspase-3, and the release of cytochrome c were abrogated in the presence of L-carnitine [52]

TGF was also found to be elevated in our patient cohort

The notable therapeutic impact of peptide-based GLP-1 derivatives in clinical neurodegenerative disorders had fostered enthusiasm among researchers to develop small molecule GLP-1RA

However, the above-mentioned results suggest that altered iron metabolism is closely related to DMD and may serve as a viable new target for clinical treatment