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It is generally believed that activation of mTORC1 by specific amino acids, notably leucine, starts with its recruitment to the lysosomal membrane by GTPases called Rags, which are concentrated there as heterodimers consisting of RagA or RagB combined with RagC or RagD

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Unit measurements at 12.5mg: 10mg/ml: 125 units (requires two injections) 20mg/ml: 62.5 units 40mg/ml: 31.25 units At 12.5mg, the 20mg/ml concentration becomes the practical minimum for single-injection dosing