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One study found statistically significant effects of the use of ALCAR over an eight to twelve week period, in improving EEG patterns and alleviating impaired brain functions in elderly patients who had mild to moderate cognitive decline

10.1371/journal.pone.0161074 87 RoncoC.HaapioM.HouseA

Alternatively, the hydrophilic portion of the linker may be pendant to or attached to the backbone of the chain of atoms connecting the binding ligand B to the one or more drugs D