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Regulatory status will remain contingent on new data and prevailing evidence standards, as well as the absence of approved therapeutic uses to date
Kostyuk VA, Potapovich AI, Cesareo E, Brescia S, Guerra L, Valacchi G, Pecorelli A, Deeva IB, Raskovic D, De Luca C, Pastore S, Korkina LG (2010) Dysfunction of glutathione S-transferase leads to excess 4-hydroxy-2-nonenal and H 2 O 2 and impaired cytokine pattern in cultured keratinocytes and blood of vitiligo patients
Keep it out of direct sunlight, away from heat sources, and in a low-humidity environment
Notably, in most countries PAC is freely sold as an OTC drug, raising the risk of unintentional abuse and increased adverse effects ( No answer can be given to the above open questions because PAC efficacy/adverse effects, unlike most of the drugs repositioned for COVID-19 therapy, have not yet been evaluated in controlled clinical trials or analyzed through retrospective analyses
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