Management: Limit use to 46 week cycles with at least equal time off Consider using GH peptides like GHRP2 or CJC1295 during off cycles to maintain baseline IGF-1 activity Risk of Unwanted Growth (Organs, Gut, Tumors) Long-term, excessive IGF1 can theoretically increase the risk of visceral organ growth , insulin resistance , or even tumor promotion , due to its role in cell proliferation
This property is especially important in targeted drugs
[DOI] [PubMed] [Google Scholar] 311.Garcia J., Boccia R.V., Graham C., Kumor K., Polvino W
Macleod SL, Nowell S, Plaxco J, Lang NP: An allele-specific polymerase chain reaction method for the determination of the D85Y polymorphism in the human UDP-glucoronosyltransferase 2B15 gene in a case-control study of prostate cancer