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As an anaerobic bacterium, it preferentially colonizes hypoxic and necrotic regions of the tumor microenvironment, making it a candidate vehicle for localized drug delivery [56]

Semax and Selank bypass the BBB entirely through intranasal administration, reaching the brain via the olfactory pathway

If a patient has low bone density, anabolic agents such as teriparatide, abaloparatide, or romosozumab may be utilized to stimulate bone formation pre-operatively to ensure the spine is strong enough to hold the new hardware

The bioavailability of morphine is therefore expected to be about 33%, which is close to the observed value (Table 31)