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Selected references Aryl Sulfonamide-Substituted 5-Amino-1-methylquinolinium Derivatives as Potent and Selective Inhibitors of Nicotinamide N-Methyltransferase (NNMT) - PubMed 2021 Nicotinamide N-methyltransferase: At the crossroads between cellular metabolism and epigenetic regulation - PubMed 2021 Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunction - PubMed 2024 Ordering Add this item to your cart, submit your shipping details at checkout, and wait for your order confirmation

During sepsis, excessive ROS production exacerbates mitochondrial dysfunction, creating a feedback loop that worsens oxidative damage (13,90)

was supported by an American Diabetes Association Womens Health Career Development Award (9-24-JDFWH-01), a MGH Physician-Scientist Development Award, and the National Institutes of Health COURAGE grant (U24 DK132733)