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Description

Omega-3 fatty acids DHA and EPA reduce bortezomib resistance in multiple myeloma cells by promoting glutathione degradation

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Mechanistically, autoantibodies and Interferon (IFN)- present in the serum enhance the binding of the transcriptional repressor cAMP-responsive element modulator alpha (CREM) to the GPX4 promoter, inducing neutrophil ferroptosis

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