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In acute respiratory distress syndrome, the shedding of the epithelial glycocalyx contributes to the development and progression of lung injury, including excessive alveolar permeability, disruption of surfactant function, greater bacterial virulence, and impaired epithelial cell repair (44)

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In the United States, Foundayo launched with a self-pay price of around $149 per month for the lowest dose, lower than the list prices of branded injectables such as Wegovy and Zepbound, though insurance and employer coverage will shape actual patient costs considerably