It creates a bridge between medicated weight management and unmedicated weight management
In the alpha cells of the islets, GLP-1 receptor activation suppresses glucagon secretion, a process mediated by somatostatin release from adjacent delta cells.54,57 Beyond the pancreas, GLP-1 receptors are widely expressed in extrapancreatic tissues, including the heart, vascular smooth muscle, lungs, liver, gastrointestinal tract, vagus nerve, and enteric nervous system.58 GLP-1 receptor agonists exhibit varying degrees of homology with endogenous GLP-1 but possess extended durations of action
Proper storage maintains the efficacy and safety of the injectable solution
Additionally, a recent Weight Watchers survey of more than 14,000 people showed that nearly half of those treated with anti-obesity medications which included GLP-1 receptor agonists as well as drugs like phentermine, bupropion/naltrexone reported a decrease in alcohol use, according to Ethan Lazarus, MD, former president of the Obesity Medicine Association
