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In a clinical trial in pediatric patients aged 12 years and older for weight reduction, cholelithiasis was reported by 3.8% of WEGOVY injection-treated patients and 0% placebo-treated patients

Commonly Observed Adverse Events Patients should be informed of the commonly-observed adverse events associated with the use of ORLISTAT which include oily spotting, flatus with discharge, fecal urgency, fatty/oily stool, oily evacuation, increased defecation, fecal incontinence [see Adverse Reactions (6.1)]

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Age, gender, race, ethnicity, and body weight do not create clinically relevant differences in how tirzepatide behaves once injected