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All these effects could lead to a potential increase in quality-adjusted life years for patients receiving HFR compared to other dialysis techniques, which would be sufficient to justify the additional cost, as has been described with other adsorptive techniques.95 Guidance for future research Despite the potential advantages of HFR over high-flux HD and OL-HDF with high convective transport, this technique could benefit from improvements in the design of currently available prototypes

Chen L, Na R, McLane KD, Thompson CS, Gao J, Wang X et al (2021) Overexpression of ferroptosis defense enzyme Gpx4 retards motor neuron disease of SOD1G93A mice

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