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Taken together, these results suggest that CPP-CAND inhibited the FOXO4-p53 interaction in the nucleus, which enabled the extranuclear transport of p53 and selectively induced apoptosis in senescent cells

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(44) found that electroacupuncture at Fengfu (GV16), Taichong (LR3), and Zusanli (ST36) modulated the SIRT3/PINK1/Parkin axis, thereby rectifying imbalances in mitophagy, promoting the clearance of damaged mitochondria, restoring mitochondrial function, and ameliorating PD symptoms