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J Chem Ecol 29:21772182 McLean MD, Yevtushenko DP, Deschene D, Van Cauwenberghe OR, Makhmoudova A, Potter JW, Bown AW, Shelp BJ (2003) Overexpression of glutamate decarboxylase in transgenic tobacco plants confers resistance to the northern root-knot nematode

Hypoxia-mediated TGF-1 expression led to the release of IL-1 and further induces TGF-1, suggesting a positive self-enhancing feedback loop between inflammation and fibrosis during myofibroblast activation