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Following the hypoxia period, the cells were reoxygenated by transferring them back to normoxic conditions (21% O 2 , 5% CO 2 ) in a standard cell culture incubator at 37C

TRX-1 has also been implicated to potentially have a mechanistic role in dauer formation via the down-regulation of the insulin-like DAF-28 signalling neuropeptide in ASJ neurons [148]