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While retinoids thicken the dermis through collagen stimulation, recent research suggests that prescription-strength tretinoin may thin the epidermis over 12+ months of continuous use, as the forced turnover eventually leads to cellular compaction
The findings compiled in this table directly inform Section 9 (Discussion) in three key areas: regarding clinical significance, it supports the prioritization of stratified interventions based on nutrients with strong evidence (e.g., dietary fiber and EPA/DHA), particularly for inflammatory depression subtypes (65, 124)
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Hepatology 55 , 11931203 (2012)
