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Currently available drugs either used alone or in combination for the treatment of RA include Glucocorticoids (GCs), NSAIDs, and DMARDs of both biological origin (such as TNF Inhibitors, IL-1, IL-6, and B cell depleting drugs) as well as synthetic (conventional like Methotrexate (MTX) and targeted like JAK-Inhibitors) (Akram et al

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