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Vladimir Khavinsons work over the past three decadesis compelling, the human clinical evidence remains limited, with most data coming from laboratory, animal, and small human studies

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Estrogen Deficiency and the Origin of Obesity during Menopause. BioMed Research International , 2014, Article ID 757461

(10) These proteins are often referred to as G-proteins, which, upon activation, might drive the generation of secondary messengers like cyclic adenosine monophosphate (cAMP) or inositol trisphosphate (IP3