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[52] Public health expert David Sencer was critical of the book, writing that it "focuses heavily on doomsday scenarios and offers little in terms of practical advice to the public" and that "a professional audience would quickly put [the book] aside for more factually correct sources of information"

Some rodent studies have actually found that animals may self-select between high-protein diets (shown to decrease overall food intake) and low-protein diets (which tend to increase overall intake) in order to meet healthy protein requirements and avoid diets that are imbalanced in amino acids

Studies have not identified direct suppression or elevation of thyroid-stimulating hormone (TSH) or free T4 levels as a primary effect of the medication

At twelve months, nearly two-thirds of the lifestyle group had lost at least 5% of their body weight