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Patients should not use if they or their family have a history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

It can be argued that the possible hypoglycemic effect is due to concomitant use of other therapies that cause hypoglycemia (eg, sulphonylurea) and it was demonstrated in clinical trials studying a combination of a GLP-1 receptor agonist and a sulphonylurea that the risk of hypoglycemia was higher when compared to placebo

First author on the study, Mark Lebwohl, MD, of the Icahn School of Medicine at Mount Sinai, New York, New York, and colleagues concluded, the findings from this trial support the multifaceted health benefits of concomitant therapy with [ixekizumab and tirzepatide] for treating psoriasis and management of comorbidities and may help to inform future clinical practice and guideline recommendations for these patients. Drs

Claims data (N=21,972) found that only 56% of patients on once-weekly GLP-1 agonists maintained a proportion of days covered (PDC) of 80% or higher at 12 months 8