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After propensity-score matching, the two cohorts (504 in each cohort, mean age 46.1 years, 57.5% women, 26.4% black, 54.7% white, 6.7% Hispanic) were balanced (see Supplementary Table S2 in the Supplementary Appendix)

Options include: Dulaglutide (Trulicity) once-weekly injection with a different molecular structure Liraglutide (Victoza) once-daily injection Exenatide (Byetta, Bydureon) twice-daily or once-weekly formulations However, if the allergic reaction was severe, many clinicians would advise avoiding the entire drug class

The most important benefit of Semaglutide for weight loss is suppressing appetite and increasing the feeling of fullness It causes a decrease in food intake