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In 2023, the FDA placed approximately 1719 peptides on the Category 2 restricted list citing safety concerns: potential carcinogenicity, immunogenicity risk, organ toxicity, and a lack of clinical trial data in humans

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Prevention of type 2 diabetes In adults with prediabetes and obesity, liraglutide 3 mg daily for three years reduced the risk of progression to type 2 diabetes by 79%, with a greater proportion reverting to normoglycaemia