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Clinical Findings of Target Organ Damage Target Organ Damage Hypertensive encephalopathy Intracranial hemorrhage Unstable angina Acute myocardial infarction Acute left ventricular failure with pulmonary edema Dissecting aortic aneurysm Eclampsia Clinical Findings Funduscopic: papilledema, hemorrhage, exudates Neurologic: somnolence, confusion, seizures, coma, visual deficits or blindness Cardiac: S4 gallop, ischemic changes on ECG, chest x-ray consistent with pulmonary edema, chest pain Renal: oliguria, progressive azotemia, hematuria, proteinuria Other: dyspnea Reprinted with permission from JNC-VII.

This supply situation has driven interest in tirzepatide alternatives and in compounded formulations that may offer more reliable availability

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The measurement forgiveness at this concentration is excellent since being off by a unit only changes your dose by 0.01mg