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Dysregulated insulin signalling and neuronal insulin resistance occurs in SNCA mutant neurons To assess the integrity of dynamic neuronal insulin signalling, day-55 post-differentiation mDA neurons were selected and cultured for a further 7 days +/-25nM exenatide, and then incubated overnight without insulin

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For example, PEG-lipid modified exenatide-loaded nanoparticles have been studied for their ability to cross mucosal barriers and improve oral bioavailability [34]

How does the dosing differ between the two