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Evidence type: Human RCT | Observational | Animal | In vitro | Regulatory Mechanism of Action AOD-9604 mimics the fat-metabolizing region of growth hormone

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Description Overview AOD9604 is a synthetic research peptide consisting of the C-terminal fragment (amino acids 177-191) of human growth hormone (hGH), with the sequence Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe

Studies have investigated NNMT inhibition in the context of obesity, metabolic dysfunction, lipid accumulation, and energy-expenditure models, with research also exploring effects on adipocyte differentiation and methylation pathways