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Toxic Multi-Nodular Goiter Another form of hyperthyroidism is toxic multi-nodular goiter, which involves the growth of independently functioning nodules on the thyroid gland itself

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However, during high-fat diet (HFD) feeding, obesity and insulin resistance, the accumulation of medium-chain and long-chain acylcarnitines due to incomplete -oxidation may negatively regulate the expression of nuclear-encoded mitochondrial genes, further reducing mitochondrial number and function and creating a vicious metabolic cycle [33]

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