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Its ability to cross the blood-brain barrier allows it to act directly on the brain

The study identifies how deficiency of the 2-oxoglutarate carrier (Slc25a11) can trigger harmful changes in retinal pigment epithelial (RPE) cellsaccelerating subretinal fibrosis, a major cause of vision loss in neovascular age-related macular degeneration (AMD)

Fisher, A

Absorption Phentermine Upon oral administration of a single QSYMIA 15 mg/92 mg, the resulting mean plasma phentermine maximum concentration (C max), time to C max (T max), area under the concentration curve from time zero to the last time with measurable concentration (AUC 0-t), and area under the concentration curve from time zero to infinity (AUC 0-) are 49.1 ng/mL, 6 hr, 1990 nghr/mL, and 2000 nghr/mL, respectively