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These kinases phosphorylate the membrane transporters (DAT, NET, SERT), leading to two outcomes: the transporters are either internalized into the cell (ceasing all reuptake function) or they undergo a conformational shift that causes them to operate in reverse

To explore the regulatory effects and mechanism of PDA@Pt on joint inflammation, we performed immunofluorescence assays on the ankle joints, assessing changes in inflammatory markers (IL-6, IL-1, TNF-) and the inflammatory signaling pathway (NF-B(P65))

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