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The NACIAM trial, a study carried out in Adelaide, revealed that early initiation of high-dose intravenous NAC in patients with myocardial infarctions (in addition to regular treatment protocols) results in significantly smaller sizes of dead heart tissue ( 10 )

Second Human Niagen Study That Demonstrates Effectiveness: A study published in PLOS One in 2017 monitored the effects of Niagen with a gradual increase in dosage. The study administered 250mg of Niagen to eight healthy volunteers on Days 1 and 2, then gradually administered higher doses each subsequent day