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As shown in the Figure above, at the end of a month, weekly nasal administration results in significantly higher serum vitamin B12 levels than after intramuscular administration

Upchurch GR Jr, Welch GN, Freedman JE, Fabian AJ, Pigazzi A, Scribner AM, et al

Role of gut-liver axis Cirrhosis is associated with dramatic alterations of the gut microbiome [64], which likely contribute to CHE pathogenesis via disruption of the gut-liver-brain axis