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Their main role is to protect the skin from damage

Clinical studies of GHK-Cu combined with 15% L-ascorbic acid demonstrate additive improvements in photoaging parameters, with combination formulations producing 35-45% greater wrinkle reductions than either agent alone

Some people experience mild side effects such as nausea, mild stomach discomfort, or digestive changes

This led to better glycemic control, increased insulin sensitivity, reduced oxidative stress, and improved kidney structure with less inflammation and fibrosis, suggesting its potential in mitigating diabetes-related renal complications (Al-Ghamdi, 2025)