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doi: 10.1016/j.arr.2016.10.005 114 FontanaLVillarealDTDasSKSmithSRMeydaniSNPittasAGet al

133 In general, the Del69/70, N501Y, D614G, and P681H of the Alpha variant were helpful to improve the infection, which can explain the high reproduction number of about 3.55.2 ( However, Del144 and N501Y affected the neutralization of antibodies, the vaccines approved by WHO showed strong neutralization ability to VOC Alpha, shown in Table 3