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For Zarghami, the early bliss of no longer thinking about or desiring food was soon replaced by concern about not being able to eat even tiny amounts like one eighth of a normal portion of scrambled eggs

Among the 16 genes, the analysis identified two for which rare mutations are known to cause monogenic obesity: MC4R and PCSK1 (proprotein convertase subtilisin/kexin type 1)

In the early stage after injury, pro-inflammatory macrophages are mainly involved in the local inflammatory reaction, which promotes the recruitment of neutrophils by secreting pro-inflammatory cytokines