Caution urged with laxative formulas and billing schemes
Natural compounds or TCM formulas with ferroptosis-inhibitory effects in other kidney diseases (e.g., berberine and paeoniflorin) have not been tested in ADPKD, representing an untapped therapeutic avenue
doi: 10.1038/nature07317 37 HolmCKRahbekSHGadHHBakROJakobsenMRJiangZet al
Maristany et al., 2024), and when finally diagnosed, patients are often labeled with phrases such as there is no cure or we will try to slow progression, while standard protocols focus primarily on symptomatic pharmacological management of proteinopathies (e.g., amyloidosis, tauopathies, prionopathies, synucleinopathies), without addressing their molecular origins (Scheltens et al., 2021)