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Over 5 years: Gastric sleeve total cost: $18,000-28,000 (one-time surgery) Retatrutide retail: $105,000 (5 years at full dose) or $52,500-63,000 (with dose reduction to maintenance levels) Retatrutide research peptides: $35,000 (5 years at full dose) or $17,500-21,000 (with dose reduction) For patients with BMI under 40, medications remain competitive with surgery

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Vision changes: If you notice any sudden changes in your vision while taking Ozempic or tirzepatide, get immediate medical attention