semaglutide effect on cholesterol of 2.4 mg use of antihypertensive and lipid‐lowering treatment in five randomized controlled STEP trials - Tchang - 2025 - Obesity Retrospective Comparative Study of Oral

GLP-1 medications accelerate fat loss overall including in the face making features appear more hollow or angular

10.1097/JIM.0000000000000129 306

Microdose GLP-1 protocols, available through PlexusDx at $129 monthly, use lower semaglutide doses to minimize side effects while maintaining therapeutic weight loss benefits for patients with medication sensitivity or gastrointestinal concerns

Whilst retatrutide is not currently available in the UK outside of clinical trials, your GP can help you understand which licensed treatments may be appropriate for your individual circumstances, taking into account your medical history, current medications, and weight management goals