Rarely, it affects younger children
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Because prostaglandins and angiotensins are used to expand the afferent arteries, anti-prostaglandin drugs such as nonsteroidal anti-inflammatory drugs (NSAIDs), drugs that have anti angiotensin activity such as angiotensin-converting enzyme inhibitors (ACEIs), or angiotensin receptor blockers (ARBs) can cause nephrotoxicity in the glomerulus Tubular cell toxicity: tubular cells are exposed to a toxic substance (nephrotoxin)
Fat around the rib cage, abdomen, and internal organs may limit lung capacity and affect breathing control