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Sodium (Na) ion transport is another essential function of astrocytes, contributing to the movement of neurotransmitters, ions and metabolites across the astrocytic membrane

Clinical Implications of ALA ALA has been used in clinical practice for 70 years to alleviate symptoms associated with various diseases, including neurodegenerative disorders, diabetes, cancer, age-related cardiovascular issues, neuromuscular conditions, weight gain caused by antipsychotic medications, and metabolic obesity [1,8,15]

Through experimental methods such as molecular docking, CESTA, and non-targeted metabolomics, we found that SAC can act on the Keap1/Nrf2/GPX4 signaling axis and regulate glutathione metabolism, effectively inhibiting ferroptosis and oxidative damage in colonic epithelial cells, thereby alleviating UC