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Although rates of acute pancreatitis have been low and similar between GLP-1 agonists and placebo in studies, caution is still warranted since acute pancreatitis carries a risk of recurrencewhich can turn into chronic pancreatitiswhich can increase risk of pancreatic cancer

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Tb-500 also upregulates vascular endothelial growth factor through HIF-1alpha stabilization, promoting angiogenesis through a pathway different from Bpc-157