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Apart from classical forms of hypogonadism, low testosterone concentrations can also be seen in older men, described as an age- and comorbidity-driven functional hypogonadism and might relate to depressive symptoms exhibiting a wide array of clinical pictures ranging from dysthymia and fatigue over inertia, listlessness to hopelessness and suicidal thoughts

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Instead, the market becomes highly complex and deeply segmented, shaped by body mass index, comorbidities, and by differences in patient profiles and preferences, including route of administration, dosing frequency and tolerability

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