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The binding of NR2B to PSD-95 contributes to dorsal horn neuron hyperexcitability and elevated pain-associated behaviors, such as hyperalgesia and allodynia, in human and animal models

102 hospitalizations

The reason this section matters even for readers who will never take NNC5840, and most readers will not, because biased-signaling agonists are years from being a consumer choice in this category, is that it changes what next-generation peptide design looks like