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This metabolism pathway via CYP450, specifically cytochrome P450 2E1 (CYP2E1), produces reactive oxygen species[17], originally thought to be the ultimate cause of liver injury in paracetamol overdose

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One 12-week study in 144 obese adults found that those who took 12 tablespoons (1530 ml) of vinegar in a diluted drink every day dropped an average 2.643.74 pounds (1.21.7 kg), while the placebo group gained weight ( A smaller study in 11 healthy adults showed that those who had vinegar with a high-carb meal had a lower blood sugar response to the food and ate 200275 fewer calories per day than people in the control group ( If consuming diluted vinegar can help decrease overall calorie intake, it may lead to weight loss over time

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