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10.1016/j.phrs.2024.107312 8 Daz-MegidoC.ThomsenM

found that quercetin indirectly prevents inflammation by enhancing peroxisome proliferator-activated receptor activity, thereby opposing NF-B or AP-1 mediated transcription of inflammatory genes, collectively obstructing the TNF--mediated inflammatory cascade and reducing inflammation damage from radiation therapy 38

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Practitioners treating obesity must adopt this evolving paradigm, incorporating early response checkpoints and tailored intervention timing to enhance patient outcomes while mitigating the discouragement and abandonment often associated with conventional treatment approaches