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And it turns out to be a fragment a small piece snipped off a much larger protein [3]

Beyond direct endocrine regulation, nutrient metabolism across the menstrual cycle is shaped by the coordinated interaction of neuroendocrine stress responses, immune signaling, gut microbial activity, intestinal barrier function, and behavior, among other factors [40,41]

*Based on an established role of extracellular NAD+ as a danger signal (Linden et al., 2019)

Nutrient interactions Interactions with vitamin K Dating back to the 1940s, studies in animals found excessive dietary intake of vitamin E was associated with fatal hemorrhaging, which was prevented with vitamin K supplementation