Structural basis for regulated assembly of the mitochondrial fission GTPase Drp1
And then secondly, you're really hindered by the idea that you're studying that animal in an artificial environment and when you reduce the risk of a subset of death, a subset of causes of death which is effectively metabolic disease, you're often unable to measure what in my opinion is an underappreciated risk that comes on, which is, sort of, the more sudden and traumatic causes of death that we take for granted, especially in the case of caloric restriction
This plan may include lipotropic injections, dietary recommendations, exercise guidelines, and other supportive measures
In addition to NAION, there is also evidence to suggest GLP-1 drugs can worsen diabetic eye disease, also known as diabetic retinopathy