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Philipot, F., Lagrange, A

Assay Type: Sandwich

Although Sorafenib is a kinase inhibitor with multiple targets including RTKs and RAF, its treatment did not affect the total tyrosyl phosphorylation and ERK phosphorylation in TamR cells (Figure S5), indicating that inhibition of TamR ER+ breast cancer cell growth by Sorafenib under the concentration used is not through inhibition of RTKs and RAF

The process is thought to be associated with: Vascular Endothelial Growth Factor (VEGF) Nitric oxide signaling Endothelial cell migration Remodeling of extracellular matrix All of these processes are vital for our body since they affect oxygen delivery and tissue maintenance