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Another possible contributing mechanism is maladaptive neuroplasticity, in which neuronal pathways adapt and conform pathologically to changes in auditory system nerve signaling

Microbiota-targeted interventions modulate peripheral and central inflammation, stabilize neurotransmitter signaling, and offer a novel pathway for modifying disease progression

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DSIP remains an intriguing area of investigation, but decades after its discovery, many fundamental questions remain unanswered