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The primary end point was melanoma-specific survival.[13][Level of evidence A1] At a follow-up of 3 years, there was no melanoma-specific survival advantage for patients randomly assigned to undergo either completion lymphadenectomy versus nodal observation with ultrasound and delayed lymphadenectomy for subsequent nodal recurrence (86% [1.3%] vs

Causes and considerations: Direct taste sensation from the copper-containing complex Post-nasal drip from nasal formulations Transient effect often mitigated with delivery technique adjustments The metallic taste is not typically a clinically meaningful adverse effect, but it can be bothersome enough that patients discontinue therapy

2026, PMID 41570941), Alzheimers neuroinflammation (Ou et al

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